We have designed a 64 electrode device to test 3C-SiC and other electrode materials. Early experiemnts utilized a device constructed from 3C-SiC and gold. PC12 cells were induced to differentiate into peripheral neurons and after 7 days in vitro the cells were activated with electrical signals driven by the device. Calcium sensitive flourescent dye was used to observe resultant calcium influx into the neurons.
  
 
Further information on the BMI project can be found using these two links.
This work is funded by:
A grant from the USF Neuroscience Collaborative (NSC),
National Institutes of Health Ruth L. Kirschstein National Research Service Award (NRSA) to C. Frewin, and
A grant from the
Florida Center of Excellence for Biomolecular Identification and Targeted Therapeutics (Now CDDI). |
